Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  KA Fund Advisors LLC
2. Date of Event Requiring Statement (Month/Day/Year)
11/23/2010
3. Issuer Name and Ticker or Trading Symbol
KAYNE ANDERSON MIDSTREAM/ENERGY FUND, INC. [KMF]
(Last)
(First)
(Middle)
1800 AVENUE OF THE STARS, SECOND FLOOR
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) __X__ Other (specify below)
See Exhibit 99.1
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

LOS ANGELES, CA 90067
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock par value $0.001 4,000
I
See Footnotes (1) (2)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
KA Fund Advisors LLC
1800 AVENUE OF THE STARS, SECOND FLOOR
LOS ANGELES, CA 90067
    X   See Exhibit 99.1
KAYNE ANDERSON CAPITAL ADVISORS LP
1800 AVENUE OF THE STARS, SECOND FLOOR
LOS ANGELES, CA 90067
    X   See Exhibit 99.1
KAYNE ANDERSON INVESTMENT MANAGEMENT INC
1800 AVENUE OF THE STARS, SECOND FLOOR
LOS ANGELES, CA 90067
    X   See Exhibit 99.1
KA Holdings Inc
1800 AVENUE OF THE STARS, SECOND FLOOR
LOS ANGELES, CA 90067
    X   See Exhibit 99.1
KAYNE RICHARD A
1800 AVENUE OF THE STARS, SECOND FLOOR
LOS ANGELES, CA 90067
    X   See Exhibit 99.1
SINNOTT ROBERT V
1800 AVENUE OF THE STARS, SECOND FLOOR
LOS ANGELES, CA 90067
    X   See Exhibit 99.1

Signatures

/s/ David J. Shladovsky, Secretary of KA Fund Advisors LLC 11/23/2010
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Direct ownership by KA Fund Advisors LLC, which purchased these shares of restricted stock to satisfy seed capital requirements.
(2) Indirect ownership by each of Kayne Anderson Capital Advisors, L.P., Kayne Anderson Investment Management, Inc., KA Holdings Inc., Mr. Kayne and Mr. Sinnott
 
Remarks:
Exhibit 24.1   Power of Attorney for KA Fund Advisors LLC
Exhibit 24.2   Power of Attorney for Kayne Anderson Capital Advisors, L.P.
Exhibit 24.3   Power of Attorney for Kayne Anderson Investment Management, Inc.
Exhibit 24.4   Power of Attorney for KA Holdings Inc.
Exhibit 24.5   Power of Attorney for Mr. Kayne
Exhibit 24.6   Power of Attorney for Mr. Sinnott
Exhibit 99.1  Relationship of Reporting Persons to Issuer

EXHIBIT 99.1: RELATIONSHIP OF REPORTING PERSON(S) TO ISSUER

KA Fund Advisors LLC is the Investment Advisor of the Issuer.  Each of Kayne Anderson Capital Advisors, L.P., Kayne Anderson Investment
Management, Inc., KA Holdings Inc., Mr. Kayne and Mr. Sinnott is an affiliate of KA Fund Advisors LLC.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

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