UNITED STATES
			SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                ----------------

                                  SCHEDULE 13G
                                 (Rule 13d-102)

             INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
           TO RULES 13d-1(b) (c) AND (d) AND AMENDMENTS THERETO FILED
                            PURSUANT TO RULE 13d-2(b)
                               (Amendment No. __)*

                            Spectrum Pharmaceuticals, Inc.
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                                (Name of Issuer)

                            Common Stock, $.001 par value
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                         (Title of Class of Securities)

                                    84763A108
             ------------------------------------------------------
                                 (CUSIP Number)

                               December 31, 2009
             ------------------------------------------------------
                  (Date of Event which Requires Filing of this
                                   Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:
                                [X] Rule 13d-1(b)
                                [ ] Rule 13d-1(c)
                                [ ] Rule 13d-1(d)

                                   Page 1 of 3

                    ----------------------------------------

* The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).



                                  SCHEDULE 13G

-------------------                                           -----------------
CUSIP No.84763A108                                           Page 2 of 3 Pages
-------------------                                           -----------------

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   1     NAME OF REPORTING PERSON
         S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

	OTA LLC
	13-3545927

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   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*         (a)   [ ]

                                                                   (b)   [ ]
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   3     SEC USE ONLY


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   4     CITIZENSHIP OR PLACE OF ORGANIZATION

         DELAWARE, USA
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                      5    SOLE VOTING POWER

                          1612619
                     ----------------------------------------------------------
    NUMBER OF         6    SHARED VOTING POWER
     SHARES
  BENEFICIALLY
    OWNED BY         ----------------------------------------------------------
      EACH            7    SOLE DISPOSITIVE POWER
    REPORTING
     PERSON                 1612619
      WITH           ----------------------------------------------------------
                      8    SHARED DISPOSITIVE POWER


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   9     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON


	 1612619
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  10     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
         SHARES*                                                         [ ]

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  11     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)


	 3.304%**
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  12     TYPE OF REPORTING PERSON

	 BD

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**Calculation of the reporting person's percentage ownership is based on an
approximate number of outstanding shares from the issuer's most recently filed
quarterly or annual report.





                                                                    Page 3 of 3

Item 1(a).  Name of Issuer:                  Spectrum Pharmaceuticals, Inc.


Item 1(b).  Address of Issuers's              157 TECHNOLOGY DR
            Principal Executive Offices:      IRVINE, CA 92618


Item 2(a).  Name of Person Filing:           OTA LLC
         			             IRS No. 13-3545927

Item 2(b).  Address of Principal Business    ONE MANHATTANVILLE ROAD
            Office or, if None, Residence:   PURCHASE, NY 10577

Item 2(c).  Citizenship:                     USA


Item 2(d).  Title of Class of Securities:    Common Stock

Item 2(e).  CUSIP Number:             	     84763A108


Item 3.   If This Statement  is Filed  Pursuant to  Rule 13d-1(b), or 13d-2(b)
            or (c), Check Whether the Person Filing is a:

      (a)   |x|   Broker or dealer registered under Section 15 of the Exchange
                  Act.

      (b)   |_|   Bank as defined in Section 3(a)(6) of the Exchange Act.

      (c)   |_|   Insurance company as defined in Section 3(a)(19) of the
                  Exchange Act.

      (d)   |_|   Investment company registered under Section 8 of the
                  Investment Company Act.

      (e)   |_|   An investment adviser in accordance with Rule
                  13d-1(b)(1)(ii)(E);

      (f)   |_|   An employee benefit plan or endowment fund in accordance with
                  Rule 13d-1(b)(1)(ii)(F);

      (g)   |_|   A parent holding company or control person in accordance with
                  Rule 13d-1(b)(1)(ii)(G);

      (h)   |_|   A savings association as defined in Section 3(b) of the
                  Federal Deposit Insurance Act;

      (i)   |_|   A church plan that is excluded from the definition of an
                  investment company under Section 3(c)(14) of the Investment
                  Company Act;

      (j)   |_|   Group, in accordance with Rule 13d-1(b)(1)(ii)(J).




Item 4.   Ownership.

     Provide  the  following  information  regarding  the  aggregate  number and
     percentage of the class of securities of the issuer identified in Item 1.

     	(a)  Amount beneficially owned:

	  	The reporting person has, as of December 31, 2009 the right to acquire
		beneficial ownership of the common stock of the issuer within 60 days
		through the exercise of 1612619 warrants. The reporting person would
		beneficially own 1612619 common shares of the issuer upon the exercise
		of these warrants.


    	 (b)  Percent of class:

	  	3.304%

		This number represents the percentage ownership based on the right to
		acquire the common stock of the issuer within 60 days upon the exercise
		of the above referenced warrants.


     	(c)  Number of shares as to which such person has:

          (i)   Sole power to vote or to direct the vote,

	        1612619
		See Item 4(a)


          (ii)  Shared power to vote or to direct the vote 0,


          (iii) Sole power to dispose or to direct the disposition of,

		1612619
		See Item 4(a)

          (iv)  Shared power to dispose or to direct the disposition of 0



Item 5.  Ownership of Five Percent or Less of a Class.

     	If this statement is being filed to report the fact that as of the date
	hereof the reporting person has ceased to be the beneficial owner of more than
	five percent of the class of securities check the following [X].



Item 6.  Ownership of More Than Five Percent on Behalf of Another Person.

         N/A

Item 7.  Identification and  Classification of the Subsidiary Which Acquired the
         Security  Being  Reported on by the Parent  Holding  Company or Control
         Person.

	 N/A

Item 8.  Identification  and  Classification  of Members of the Group.

         N/A

Item 9.  Notice of Dissolution of Group.

         N/A

Item 10.  Certifications.

|X|  (a)  The  following  certification  shall be included if the  statement  is
          filed pursuant to Rule 13d-1(b):

          "By signing  below I certify  that,  to the best of my  knowledge  and
          belief, the securities referred to above were acquired and are held in
          the ordinary course of business and were not acquired and not held for
          the  purpose  of or with the effect of  changing  or  influencing  the
          control of the issuer of the  securities and were not acquired and are
          not held in  connection  with or as a participant  in any  transaction
          having such purpose or effect."

     (b)  The  following  certification  shall be included if the  statement  is
          filed pursuant to Rule 13d-1(c):

          "By signing  below I certify  that,  to the best of my  knowledge  and
          belief, the securities referred to above were not acquired and are not
          held for the purpose of or with the effect of changing or  influencing
          the control of the issuer of the  securities and were not acquired and
          are not held in connection with or as a participant in any transaction
          having such purpose or effect."

	After  reasonable  inquiry and to the best of my  knowledge  and belief,  I
certify that the information  set forth in this statement is true,  complete and
correct.


               					    January 08, 2010
                                         ---------------------------------------
                                                         (Date)


                                               /s/  JOHN HANRATTY
                                         ---------------------------------------
                                                       (Signature)


                                         JOHN HANRATTY, CHIEF COMPLIANCE OFFICER
                                         ---------------------------------------
                                                      (Name/Title)


Note.  Schedules  filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See Rule 13d-7 for other parties
for whom copies are to be sent.

Attention.  Intentional  misstatements  or omissions of fact constitute  federal
criminal violations (see 18 U.S.C. 1001).