FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * Valentine Keith   2. Issuer Name and Ticker or Trading Symbol SeaSpine Holdings Corp [SPNE] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) Chief Executive Officer (Last) (First) (Middle) C/O SEASPINE HOLDINGS CORPORATION, 5770 ARMADA DRIVE 3. Date of Earliest Transaction (Month/Day/Year) 12/31/2018 (Street) CARLSBAD, CA 92008 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 12/31/2018   J(1) V 1,206 A $ 6.426 (2) 184,276 D   Common Stock 01/01/2019   M   35,938 A (3) 220,214 D   Common Stock 01/01/2019   M   27,428 A (3) 247,642 D   Common Stock 01/01/2019   F   23,611 (4) D $ 18.24 224,031 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Restricted Stock Units

(3)

01/01/2019

M

35,938

(5)

(5)

Common Stock

35,938

$ 0

35,939

D

Restricted Stock Units

(3)

01/01/2019

M

27,428

(6)

(6)

Common Stock

27,428

$ 0

54,856

D

Restricted Stock Units

(3)

01/01/2019

A

23,365

(7)

(7)

Common Stock

23,365

$ 0

23,365

D

Employee Stock Option (Right to Buy)

$ 18.24

01/01/2019

A

77,881

(8)

01/01/2027

Common Stock

77,881

$ 0

77,881

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Valentine Keith C/O SEASPINE HOLDINGS CORPORATION 5770 ARMADA DRIVE CARLSBAD, CA 92008	X		Chief Executive Officer

Signatures

/s/ Paul Benny, Attorney-in-Fact for Keith C. Valentine		01/03/2019
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	These shares were acquired under the issuer's 2015 Employee Stock Purchase Plan (ESPP) in transactions that were exempt under Rule 16b-3(c).
(2)	In accordance with the ESPP, these shares were purchased based on 85% of the closing price of the issuer's common stock on January 3, 2017, which was the first trading day of the applicable offering period.
(3)	Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.
(4)	These shares were withheld by the issuer to satisfy statutory tax withholding requirements on vesting of restricted stock units that occurred on January 1, 2019. No shares were sold in connection with this transaction.
(5)	The reporting person was granted 107,815 restricted stock units on February 2, 2017, which vest in three equal installments on each of January 1, 2018, 2019 and 2020.
(6)	The reporting person was granted 82,284 restricted stock units on March 5, 2018, which vest in three equal installments on each of January 1, 2019, 2020 and 2021.
(7)	The restricted stock units vest in three equal installments on each of January 1, 2020, 2021 and 2022.
(8)	The option vests as to 25% of the underlying shares on January 1, 2020 and the remaining 75% in twelve substantially equal quarterly installments thereafter.

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