AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON AUGUST 22, 2003

                                             REGISTRATION NO.  333-____________

                UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM S-3

             REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

                                  I-TRAX, INC.
                   ------------------------------------------
             (Exact name of registrant as specified in its charter)

                                    Delaware
                   ------------------------------------------
         (State or other jurisdiction of incorporation or organization)

                                   23-3057155
                   ------------------------------------------
                      (I.R.S. Employer Identification No.)

                          ONE LOGAN SQUARE, SUITE 2615
                               130 N. 18TH STREET
                        PHILADELPHIA, PENNSYLVANIA 19103
                                 (215) 557-7488
 -------------------------------------------------------------------------------
   (Address, including zip code, and telephone number, including are code, of
                    registrant's principal executive offices)

                                 FRANK A. MARTIN
                      CHAIRMAN AND CHIEF EXECUTIVE OFFICER
                                  I-TRAX, INC.
                  ONE LOGAN SQUARE, SUITE 2615, 130 N. 18TH ST.
                             PHILADELPHIA, PA 19103
                               (215) 557-7488 x110
 -------------------------------------------------------------------------------
 (Name, address, including zip code, and telephone number, including are code,
                             of agent for service)

                                   COPIES TO:

YURI ROZENFELD, ESQ.                     JUSTIN P. KLEIN, ESQ.
GENERAL COUNSEL                          GERALD GUARCINI, ESQ.
I-TRAX, INC.                             BALLARD SPAHR ANDREWS & INGERSOLL, LLP
ONE LOGAN SQUARE, SUITE 2615             1735 MARKET STREET, 51ST FLOOR
130 N. 18TH ST.                          PHILADELPHIA, PA  19103
PHILADELPHIA, PA 19103                   (215) 665-8500
(215) 557-7488 x116

Approximate date of commencement of proposed sale to the public: As soon as
practicable after the effective date of this registration statement.

If the only securities being registered on this Form are being offered pursuant
to dividend or interest reinvestment plan, please check the following box. [ ]

If any of the securities being registered on this Form are to be offered on a
delayed or continuous basis pursuant to Rule 415 under the Securities Act of
1933, other than securities offered only in connection with dividend or interest
reinvestment plans, check the following box. [X]




      If this Form is filed to register  additional  securities  for an offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list  the  Securities  Act  registration  statement  number  of the  earlier
effective registration statement for the same offering. [ ]

      If this Form is a  post-effective  amendment filed pursuant to Rule 462(c)
under the  Securities  Act,  check the following box and list the Securities Act
registration  statement number of the earlier effective  registration  statement
for the same offering. [ ]

      If delivery of the prospectus is expected to be made pursuant to Rule 434,
please check the following box. [ ]





                         Calculation of Registration Fee

   Title of each class of                            Proposed maximum
securities to be registered       Amount to be      offering price (2)      Proposed Maximum           Amount of
                                 registered (1)                         aggregate offering price   registration fee
                 
Common stock, value $.001
per share                         1,635,295 shares        $2.82                       $4,611,532              $373.07
----------------------------- --------------------- ------------------- ------------------------- --------------------




(1) The amount to be registered  includes shares of outstanding common stock and
shares of common stock issuable upon  conversion of an  outstanding  convertible
promissory  note and  exercise of  outstanding  warrants.  The actual  number of
shares of common stock registered in this registration  statement  includes such
additional  number of shares of  common  stock as may be issued or  issuable  by
reason of any stock split, stock dividend or similar  transaction  involving the
common stock,  in accordance  with Rule 416 under the Securities Act of 1993, as
amended.

(2) Estimated  solely for purposes of calculating the amount of the registration
fee  pursuant  to Rule 457(c) of the  Securities  Act of 1933,  as amended.  The
registration  fee is calculated  on the basis of $2.82,  the average of the high
and low prices for our common stock as traded on the American  Stock Exchange on
August 20, 2003.



                                        2




         The  information in this  prospectus is not complete and may be changed
         without  notice.   We  may  not  issue  these   securities   until  the
         registration   statement   filed  with  the   Securities  and  Exchange
         Commission is effective.  This prospectus is not an offer to sell these
         securities and we are not soliciting  offers to buy these securities in
         any jurisdiction where the offer or sale is not permitted.


                  SUBJECT TO COMPLETION, DATED AUGUST 22, 2003

                                   PROSPECTUS

                                  I-TRAX, INC.

                                    1,635,295

                                    SHARES OF

                                  COMMON STOCK

         This prospectus relates to the offer and sale from time to time of the
following share held by the selling shareholders:

            o           up to 1,218,628 shares of our common stock; and

            o           up to 416,667  shares of common stock  issuable upon the
                        exercise of  outstanding  warrants and  conversion  of a
                        convertible promissory note.

      The  prices at which  selling  shareholders  may sell the  shares  will be
determined  by the  prevailing  market  price for the  shares  or in  negotiated
transactions.  We will  not  receive  any of the  proceeds  from the sale of the
shares.

      The shares offered by this prospectus were originally issued in connection
with several private placements of our securities.

      Our common stock is listed on the American Stock Exchange under the symbol
"DMX." On August 20, 2003, the closing price for our common stock was $2.80.

      Investing in our common stock involves  risks,  which are described in the
"Risk Factors" section beginning on page 6 of this prospectus.

                        ________________________________

      Neither the  Securities and Exchange  Commission nor any state  securities
commission has approved or disapproved of these securities or determined if this
prospectus  is truthful or  complete.  Any  representation  to the contrary is a
criminal offense.

                        ________________________________


                  The date of this Prospectus is ____ __, 2003






                                TABLE OF CONTENTS


Preliminary Notes.....................................................  2
Statement Regarding Forward-Looking Information.......................  2
I-trax, Inc...........................................................  3
Risk Factors..........................................................  6
Market for Common Equity.............................................. 13
Use of Proceeds....................................................... 13
Selling Security Holders.............................................. 14
Plan of Distribution.................................................. 15
Available Information................................................. 16
Incorporation of Certain Documents by Reference....................... 16
Legal Matters......................................................... 17
Experts............................................................... 17


                                PRELIMINARY NOTES

      You should rely only on the  information  contained  and  incorporated  by
reference in this  prospectus.  No one has been  authorized  to provide you with
different  information.  This prospectus is not an offer of these  securities in
any state  where the offer is not  permitted.  You should  not  assume  that the
information contained and incorporated by reference in this prospectus or in any
prospectus  supplement  is  accurate  as of any date  other than the date on the
front of the document.

      Unless  otherwise  indicated,  references to "we," "our" and "I-trax" mean
I-trax, Inc. and its subsidiaries.

      Effective January 3, 2003, we completed a 1-for-5 reverse stock split. Our
board of  directors  and  stockholders  authorized  the  reverse  stock split in
connection  with the then  pending  application  to list our common stock on the
American  Stock  Exchange.  Our common stock began trading on the American Stock
Exchange on January 15, 2003 under the symbol "DMX." The  information  presented
in this  prospectus  about the number of outstanding  shares of our common stock
and  historic  information  about our  common  stock and stock  prices  has been
adjusted to reflect the completed reverse stock split.

                 STATEMENT REGARDING FORWARD LOOKING INFORMATION

      This   prospectus  and  our  filings  with  the  Securities  and  Exchange
Commission  (or  SEC)  incorporated  by  reference  in this  prospectus  include
forward-looking statements. All statements,  other than statements of historical
facts,  included in this prospectus and our filings with the SEC incorporated by
reference  in  this  prospectus  regarding  our  strategy,   future  operations,
financial  position,  future  revenues,  projected costs,  prospects,  plans and
objectives   of   management   are   forward-looking   statements.   The   words
"anticipates,"  "believes,"  "estimates,"  "expects," "intends," "may," "plans,"
"projects,"  "will,"  "would" and similar  expressions  are intended to identify
forward-looking statements,  although not all forward-looking statements contain
these  identifying  words. We cannot guarantee that we actually will achieve the
plans,  intentions or expectations  disclosed in our forward-looking  statements
and you should  not place  undue  reliance  on our  forward-looking  statements.
Actual results or events could differ materially from the plans,  intentions and
expectations  disclosed  in the  forward-looking  statements  we  make.  We have
included important factors in the cautionary statements included or incorporated
in this prospectus,  particularly  under the heading "Risk Factors" beginning on
page 6 below  that we believe  could  cause  actual  results or events to differ
materially  from the  forward-looking  statements we make.  Our  forward-looking
statements  do not  reflect  the  potential  impact of any future  acquisitions,
mergers, dispositions, joint ventures or investments we may make.


                                      -2-




                                  I-TRAX, INC.

Business Overview

         I-trax enables better healthcare through personalized health management
programs.

      We  believe  that  our  personalized   disease  and  lifestyle  management
solutions  enable  organizations  to  evolve  from  fragmented  care  management
practices into a cohesive and efficient system of healthcare.  Our solutions are
fully integrated, use a single-data platform that allows all caregivers to share
records, and enable our clients to provide true coordination of care. We believe
that by facilitating  real-time  communication  between all stakeholders  within
today's complex  healthcare  system,  our solutions  reduce costs and enable the
best possible delivery of care.

      Health-e-LifeSM Program

      We deliver our solutions through our proprietary  Health-e-LifeSM Program.
The  Program  is  designed  to deliver  lifestyle,  disease  and risk  reduction
interventions  to  an  entire  population  by  utilizing   predictive   science,
technology, clinical expertise and personal care coordination.

      Predictive Science

      Our Health-e-LifeSM Program incorporates predictive science to analyze our
clients'  medical  claims and  pharmacy  and  clinical  data to  predict  future
healthcare  costs. We believe this is an essential step to effective disease and
lifestyle   management.   Experts  agree  that  predictive  science  provides  a
comprehensive  advantage to health plans, employers and providers,  and leads to
cost effective medical  management and greater  profitability.  Using predictive
science,  we analyze our clients' entire  populations to accurately  predict our
clients'  future  healthcare  costs,   including  avoidable  costs,  the  health
conditions  that will  drive  those  costs and the people  within  our  clients'
populations who are at risk for those  conditions.  Armed with this information,
I-trax is able to target the most  appropriate  resources  to  achieve  the best
savings and return on investment.

      Technology Solutions

      All technology components of our Health-e-LifeSM  Program utilize a single
data   platform--Medicive(R)   Medical  Enterprise  Data  System--a  proprietary
software architecture developed to collect,  store, retrieve and analyze a broad
range of information used in the healthcare industry.

      Further, our web accessible solutions include portals for key stakeholders
in the care  delivery  process--consumers,  physicians  and care  managers--thus
permitting  real-time  sharing of  information  and support the adherence to our
health  and  disease  intervention  programs.  The  key  technology  we use  for
effective care coordination include:

      o     Health-e-Coordinator(TM), a web-based care management application;
      o     MyFamilyMD(TM), a consumer health management portal;
      o     CarePrime(R),   a  clinical  care  application  for  physicians  and
            clinicians; and
      o     I-talk(TM), interactive smart voice technology.

      Interventions and Clinical Expertise

      Our  personalized  health  and  disease  interventions  include  intensive
programs for  individuals  who suffer from,  or are at high risk for,  active or
chronic  disease and  tailored  programs  for  individuals  who are at low risk.
Depending on the individual's  level of risk, our custom tailored  interventions
include self-help programs available through the web or person-assisted programs
administered through our Care Communication  Center, which is staffed by trained
nurses and other healthcare professionals 24 hours per day, 7 days per week. All
interventions   include  lifestyle  and  risk  reduction  programs  that  follow
evidence-based clinical guidelines to optimize health, fitness, productivity and
quality of life.


                                      -3-



      We have  designed  and are  implementing  interventions  for a  number  of
specific chronic conditions,  including congestive heart failure (CHF), coronary
artery disease (CAD),  asthma,  diabetes,  cancer  management,  cystic fibrosis,
lower back pain and chronic obstructive pulmonary disease (COPD).

      Care Communication Center

      Our Care  Communications  Center is staffed with trained  nurses and other
healthcare  professionals 24 hours per day, 7 days per week. Through the Center,
we effect  targeted  interventions  to  improve  the  health  management  of the
populations we serve.  The Center helps consumers make informed  decisions about
their health and provides ongoing support for those with chronic  diseases.  Our
demand management and nurse triage services incorporate  nationally  recognized,
evidence-based  clinical  guidelines to ensure that all caregivers and consumers
are following the best practices.

      Everything we do is built on information, which drives decision-making and
results.  Information guides the identification of consumers, the utilization of
protocols that provide high quality and cost effective  care, the  communication
among the key  stakeholders  and  ultimately  the return on capital  invested in
providing healthcare. When all of these components are in place, we believe that
consumer   satisfaction  will  increase  and  the  costs  of  providing  quality
healthcare will decrease.

Corporate Information

         General

      Our principal  executive  offices are located at One Logan Square,  130 N.
18th Street, Suite 2615, Philadelphia,  Pennsylvania 19103. Our telephone number
is (215)  557-7488 and our fax number is (215)  557-7820.  We maintain a website
located at  http://www.i-trax.com.  Information  contained on our website is not
part of this prospectus.

      We make our  annual  reports  on Form  10-KSB,  quarterly  reports on Form
10-QSB  and  current  reports  on Form  8-K,  as well as any  amendments  to the
forgoing,  available  free of  charge  on our  website  as  soon  as  reasonably
practicable after they have been filed with the SEC. For a detailed  description
of our business you should read these reports and the other filings we make with
the SEC which are incorporated by reference in this prospectus.

      I-trax, Inc.--Holding Company

      I-trax was  incorporated in the State of Delaware on September 15, 2000 at
the direction of the board of directors of I-trax Health  Management  Solutions,
Inc. (or Health Management),  I-trax's then parent company. On February 5, 2001,
I-trax  became the  holding  company of Health  Management  at the  closing of a
reorganization  pursuant to Section 251(g) of Delaware General  Corporation Law.
The holding company  reorganization  was described in greater detail in I-trax's
registration  statement on Form S-4 (Registration Number 333-48862),  filed with
the SEC on October 27, 2000. At the effective time of the  reorganization all of
the  stockholders  of Health  Management  became the  stockholders of I-trax and
Health  Management  became a wholly owned  subsidiary  of I-trax.  Further,  all
outstanding  shares of Health Management were converted into shares of I-trax in
a non-taxable  transaction.  Health  Management no longer files reports with the
SEC.  However,  I-trax does file  reports  with the SEC, and its common stock is
traded on the American Stock Exchange under the symbol "DMX."

      The holding  company  structure has allowed us greater  flexibility in our
operations and expansion and diversification plans, including in the acquisition
of WellComm  Group,  Inc. on February 6, 2002 and iSummit  Partners,  LLC, doing
business as "MyFamilyMD," on February 7, 2001.

      I-trax  acquired  WellComm  effective  February  6,  2002  in  a  two-step
reorganization  pursuant  to a Merger  Agreement  dated  January 28, 2002 by and
among I-trax, WC Acquisition,  Inc., an Illinois  corporation and a wholly-owned
subsidiary of I-trax,  WellComm and WellComm's two principals.  The initial step
of the reorganization  transaction  involved a merger of WC Acquisition with and
into WellComm, in which merger WellComm continued as the surviving  corporation.
The second step of the reorganization transaction involved a statutory merger of
WellComm with and into I-trax, in which merger I-trax continued as the surviving
corporation.


                                      -4-



      At the  closing of the  WellComm  merger,  we  delivered  to the  WellComm
stockholders approximately $2,200,000 in cash and 1,488,000 shares of our common
stock,  and to each of two senior officers of WellComm options to acquire 56,000
shares of our common stock at a nominal exercise price. After the merger,  three
executive officers of WellComm joined us as senior executives and WellComm's two
principal stockholders were elected to our board of directors.

      We funded the  acquisition of WellComm by selling a 6% convertible  senior
debenture  in  the  aggregate   principal   amount  of  $2,000,000  to  Palladin
Opportunity  Fund LLC pursuant to a Purchase  Agreement  dated as of February 4,
2002 between Palladin and us. Pursuant to the purchase agreement, we also issued
Palladin a warrant to purchase  up to 307,692  shares of our common  stock.  The
outstanding  principal and any interest  under the debenture are payable in full
on or before February 3, 2004. Further,  outstanding  principal and any interest
may be converted at any time at the election of Palladin  into our common stock.
The  conversion  price under the  debenture,  and the  exercise  price under the
warrant, is $1.75.

      I-trax  acquired  iSummit  effective  February  7,  2001  in  an  exchange
transaction  pursuant to a Contribution  and Exchange  Agreement dated September
22, 2000,  as amended,  by and among  iSummit,  I-trax,  Health  Management  and
iSummit's three members. I-trax issued 580,682 shares of common stock to acquire
iSummit (reflecting a post closing adjustments to the aggregate number of issued
shares effective as of December 31, 2001).

      I-trax Health Management Solutions, Inc.--Operating Subsidiary

      Health  Management  is a  predecessor  to  I-trax  and  is  our  operating
subsidiary.  It was  incorporated  in the  State of  Delaware  under the name of
Marmac  Corporation  in May 1969. In December  1979, it changed its name to Ibex
Industries International, Inc. On April 1, 1996, Health Management purchased the
assets  of  certain  physician  practices,  changed  its  name to  U.S.  Medical
Alliance,  Inc.,  and commenced  operations as a physician  practice  management
company.

      As U.S.  Medical  Alliance,  Health  Management  completed one  additional
physician practice  acquisition.  However, it did not have adequate liquidity or
capital resources to withstand the downturn in the physician practice management
industry, nor the ability to acquire profitable physician practices.  In January
1997, the board of directors of Health  Management,  in an effort to reorganize,
elected Frank A. Martin as its  President.  Mr. Martin  negotiated the return of
the previously  acquired physician practice assets to the physicians in exchange
for the cancellation of any Health Management  capital stock or notes associated
with those acquisitions.  Health Management changed its name to I-Trax.com, Inc.
in August 1999.

      Health  Management  merged with  Member-Link  effective  December 30, 1999
pursuant to a Merger  Agreement  dated as of December 14,  1999.  In the merger,
Health  Management  issued an aggregate of 1,554,368 shares (as adjusted) of its
common stock. On February 7, 2001,  Health  Management and I-trax  completed the
previously described holding company  reorganization.  Health Management assumed
its current name, I-trax Health Management Solutions, Inc., on March 21, 2001.



                                      -5-





                                  RISK FACTORS

      In addition to other information  contain and incorporated by reference in
this prospectus, you should carefully consider the following risks and the other
information  in  evaluating  I-trax and its business.  Our  business,  financial
condition and results of operations  could be materially and adversely  affected
by each of these risks.  Such an adverse  effect could cause the market price of
our common stock to decline, and you could lose all or part of your investment.

Risk Related to I-trax

      We have a history of operating losses and anticipate  continued  operating
      losses through the third quarter of 2003.

      We have used  substantial cash to fund our operating  losses,  and we have
never earned a profit.  Through June 30, 2003, we have used approximately $ 14.4
million of cash to fund our  operating  activities.  Moreover,  we expect to use
additional cash to fund our operating  losses through the third quarter of 2003.
Our ability to achieve profitability will depend, in part, on:

      o     the commercial success of our service and software applications;

      o     successful  deployment  and  retention  of our services and software
            applications by our customers; and

      o     our sales and marketing activities.

      The success of our business model depends on attracting customers, such as
public health agencies,  hospitals,  health plans,  self-insured employers,  and
colleges  and  universities,  to our  population  health  management  solutions.
Although  we believe  that this  business  model will be  successful,  we cannot
assure you that we will achieve or sustain  profitability  or that our operating
losses will not increase in the future.

      We will  require  additional  capital  to fund our  operating  losses  and
      improve our products and services.

      Additional funds are required to complete our planned product  development
efforts, expand our sales and marketing activities, and to cover cash shortfalls
until our current and projected pipeline materializes.  At present, we expect to
obtain  such  funds  from  operations  and  financings   activities.   Financing
activities  may include  equity or debt  financings,  strategic  alliances  with
corporate  partners and others,  or through  other  sources.  We cannot  provide
assurance that additional  funding will be available on acceptable  terms, if at
all. If adequate  funds are not available,  we may have to delay,  scale-back or
eliminate  certain  aspects of our operations or attempt to obtain funds through
arrangements with collaborative partners or others.  Moreover, if we continue to
have operating  losses and are unable to obtain capital to cover them, we may be
unable  to  remain  in  business.  These  results,  in  turn,  could  cause  the
relinquishment  of our  rights  to  certain  of our  technologies,  products  or
potential  markets,  dilution of your ownership in our business,  or our loss of
what we  believe  is a  current  competitive  advantage  in  technology  enabled
population health management field. Therefore,  the inability to obtain adequate
funds could have a material adverse impact on our business,  financial condition
and results of operations.

      The segment of the  healthcare  industry in which we operate is relatively
      new and our sales cycle is long and complex.

      The disease and population  health management  business,  although growing
rapidly,  is a relatively new segment of the overall healthcare industry and has
many entrants.  Many companies use the generic label of "disease  management" to
characterize  activities  ranging from the sale of medical supplies and drugs to
services aimed at managing demand for healthcare services.  Because this segment
of the industry is  relatively  new,  potential  purchasers  take a long time to
evaluate and purchase such services,  lengthening our sales cycle.  Further, the
sales and implementation  process for our services and software  applications is
lengthy,  involves a significant technical evaluation and requires our customers
to commit a great deal of time and money.  Finally,  the sale and implementation
of our solutions are subject to delays due to our  customers'  internal  budgets
and  procedures  for


                                      -6-



approving  large  capital  expenditures  and deploying new services and software
applications  within  their  organizations.  The sales cycle for our  solutions,
therefore,  is  unpredictable  and has generally ranged from 3 to 24 months from
initial  contact  to  contract  signing.  The  time it takes  to  implement  our
solutions is also  difficult to predict and has lasted as long as 18 months from
contract execution to the commencement of live operation. During the sales cycle
and the implementation  period, we may expend substantial time, effort and money
preparing  contract  proposals,  negotiating the contract and  implementing  the
solution without receiving any related revenue.

      Our limited  operating  experience may cause us to misjudge the segment of
      the healthcare industry in which we are operating.

      We have only recently begun to design,  build and offer disease management
and  comprehensive   health  management   solutions.   Our  enterprise  software
applications  have been  operational  for less than four  years,  our  web-based
solutions  have  been  operational  for less  than  two  years  and our  disease
management and comprehensive  health management  solutions have been operational
for only one year.  Accordingly,  we have a  limited  operating  history  in our
business. Furthermore, we are also facing other risks and challenges,  including
a lack of  meaningful  historical  financial  data  upon  which  to plan  future
budgets,  increasing competition,  the need to develop strategic  relationships,
and  other  risks  described  below.  We cannot  guarantee  that we will be able
successfully  to implement our business  model.  An investor in our common stock
must consider the risks,  uncertainties,  expenses and  difficulties  frequently
encountered  by companies in their early stages of  development.  As a result of
the absence of meaningful history and experience in our business,  we may easily
misjudge the nature or size of our perceived  markets,  or the amount of work or
capital  necessary to complete our pending products or to implement our business
plan.

         We may be unable to  implement  our  business  strategy  to deploy  our
         products  effectively  and  attract customers.

      Although we believe that there is significant  demand for our services and
products in the overall healthcare market,  there are many reasons why we may be
unable to execute our business strategy, including our possible inability to:

      o     deploy our services and software applications on a large scale;

      o     attract a  sufficiently  large  number of  public  health  agencies,
            hospitals,  health  plans,  self-insured  employers and colleges and
            universities   to   subscribe   for  our   services   and   software
            applications;

      o     increase awareness of our brand;

      o     strengthen user loyalty;

      o     develop and improve our services and software applications;

      o     continue  to  develop  and  upgrade  our   services   and   software
            applications; and

      o     attract, retain and motivate qualified personnel.

      The healthcare industry is subject to cost pressures.

      The healthcare  industry is currently under pressure by  governmental  and
private-sector  revenue  sources to cut spiraling  costs.  These  pressures will
continue  and  possibly  intensify.  Although we believe  that our  services and
software applications assist public health agencies, hospitals, health plans and
self-insured  employers to control the high costs  associated with the treatment
of chronic  diseases,  the pressures to reduce costs  immediately may hinder our
ability (or the length of time we require) to obtain new contracts. In addition,
the focus on cost reduction may pressure our customers to restructure  contracts
and reduce our fees.


                                      -7-




         Government regulation could adversely affect our business.

      Many of our existing  and  potential  clients are subject to  considerable
state and federal government regulations.  Many of these regulations are vaguely
written and subject to  differing  interpretations  that may, in certain  cases,
result in  unintended  consequences  that may affect our ability to  effectively
deliver our services.  Regulatory and legislative efforts currently focus on the
confidentiality of patient  identifiable  medical  information,  as evidenced by
such legislation as the Health Insurance  Portability and  Accountability Act of
1996  (or  HIPAA).   While  we  believe  that  our  ability  to  obtain  patient
identifiable medical information for disease management purposes from certain of
our clients is  protected in recently  released  federal  regulations  governing
medical record  confidentiality,  state  legislation or regulations will preempt
federal legislation if it is more restrictive. Accordingly, new federal or state
legislation or regulations  restricting the  availability of this information to
us or leaving  uncertain  whether  disease  management  is an  allowable  use of
patient  identifiable  medical information would have a material negative effect
on us.

      Although we are not directly subject to many of the regulations  governing
healthcare  delivery,  our clients,  such as public health agencies,  hospitals,
health plans, and self-insured employers, must comply with regulations including
the  licensing  and  reimbursement  requirements  of  federal,  state  and local
agencies.  Further,  certain of our professional  healthcare employees,  such as
doctors and nurses, are subject to individual licensing requirements. All of our
healthcare  professionals who are subject to licensing requirements are licensed
in the state in which they are  physically  present.  Multiple  state  licensing
requirements for healthcare  professionals  who provide services  telephonically
over state lines may require us to license some of our healthcare  professionals
in more than one state. We continually monitor the developments in telemedicine.
There is no assurance,  however, that new judicial decisions or federal or state
legislation or regulations  would not increase the  requirement  for multi-state
licensing of all central operating unit call center health professionals,  which
would significantly increase our administrative costs.

      We are indirectly  affected by changes in the laws governing  health plan,
hospital and public health agency reimbursement under governmental programs such
as  Medicare  and  Medicaid.  There  are  periodic  legislative  and  regulatory
initiatives  to reduce the funding of the Medicare  and Medicaid  programs in an
effort to  curtail  or  reduce  overall  federal  healthcare  spending.  Federal
legislation has and may continue to  significantly  reduce Medicare and Medicaid
reimbursements  to most hospitals.  These  reimbursement  changes are negatively
affecting hospital revenues and operations.  There can be no assurance that such
legislative initiatives or government regulations would not adversely affect our
operations or reduce demand for our services.

      Various federal and state laws regulate the  relationship  among providers
of healthcare services,  other healthcare businesses and physicians.  The "fraud
and abuse"  provisions  of the Social  Security  Act provide  civil and criminal
penalties and potential  exclusion  from the Medicare and Medicaid  programs for
persons or businesses who offer,  pay, solicit or receive  remuneration in order
to induce  referrals of patients covered by federal  healthcare  programs (which
include Medicare, Medicaid, TriCare and other federally funded health programs).
Although  we believe  that our  business  arrangements  with our  clients are in
compliance  with these  statutes,  these fraud and abuse  provisions are broadly
written  and the full  extent  of their  application  is not yet  known.  We are
therefore  unable  to  predict  the  effect,   if  any,  of  broad   enforcement
interpretation of these fraud and abuse provisions.

      Our dependence on the Internet and Internet-related  technologies subjects
      us to frequent change and risks.

      Our web-based software  applications that form the backbone of our disease
management  and  comprehensive   health  management   solutions  depend  on  the
continuous,  reliable  and secure  operation  of  Internet  servers  and related
hardware and software.  In the past,  several large Internet commerce  companies
have suffered highly  publicized  system  failures,  which depressed their stock
prices,  caused significant  negative publicity and sometimes led to litigation.
It is possible that we may also suffer service outages from time to time. To the
extent that our service is interrupted, our users will be inconvenienced and our
reputation may be diminished.  If access to our system becomes  unavailable at a
critical time,  users could allege we are liable,  which could depress our stock
price,  cause  significant  negative  publicity and possibly lead to litigation.
Although our computer and  communications  hardware is protected by physical and
software  safeguards,  it is still vulnerable to fire, storm, flood, power loss,
telecommunications  failures, physical or software break-ins and similar events.
We will not have 100%


                                      -8-



redundancy  for  all  of  our  computer  and  telecommunications  facilities.  A
catastrophic  event could have a  significant  negative  effect on our business,
results of operations, and financial condition.

      We also depend on third  parties to provide  certain of our  clients  with
Internet and online services necessary for access to our servers. It is possible
that our clients will  experience  difficulties  with  Internet and other online
services due to system failures,  including  failures  unrelated to our systems.
Any sustained disruption in Internet access provided by third parties could have
a material  adverse effect on our business,  results of operations and financial
condition.

      Finally, we retain confidential  healthcare information on our servers. It
is, therefore, critical that our facilities and infrastructure remain secure and
are  perceived  by clients  to be  secure.  Although  we  operate  our  software
applications  from a secure  facility  managed by a reputable  third party,  our
infrastructure  may be  vulnerable  to  physical  break-ins,  computer  viruses,
programming  errors or similar disruptive  problems.  A material security breach
could damage our reputation or result in liability to us.

      We may be sued by our users if we provide inaccurate health information on
      our  website  or  inadvertently  disclose  confidential  health
      information to unauthorized users.

      Because  users of our website  will  access  health  content and  services
relating to a medical  condition  they may have or may distribute our content to
others,  third  parties  may sue us for  defamation,  negligence,  copyright  or
trademark  infringement,  personal injury or other matters. We could also become
liable if confidential information is disclosed inappropriately.  These types of
claims have been brought, sometimes successfully, against online services in the
past.  Others  could  also sue us for the  content  and  services  that  will be
accessible  from our website  through links to other websites or through content
and materials that may be posted by our users in chat rooms or bulletin  boards.
Any such liability will have a material adverse effect on our reputation and our
business, results of operations or financial position.

      Our business will be adversely  affected if we lose a key employee or fail
      to recruit and retain other skilled employee.

      Our Chairman and Chief Executive Officer,  Frank A. Martin, is an integral
part of our business and our future success  greatly depends upon his retention.
Our  failure to retain Mr.  Martin  could  significantly  reduce our  ability to
compete and succeed in the future.

      Our future  success  also  depends on our ability to  attract,  retain and
motivate highly skilled employees.  As we secure new contracts and implement our
services  and  products,  we  will  need  to hire  additional  personnel  in all
operational areas. We may be unable to attract, assimilate or retain such highly
qualified  personnel.  We  have  in  the  past  experienced,  and we  expect  to
experience  in the future,  difficulty in hiring and  retaining  highly  skilled
employees with  appropriate  qualifications.  If we do not succeed in attracting
new personnel or retaining and  motivating our current  personnel,  our business
will be adversely affected.

      We may be  unable  to  compete  successfully  against  companies  offering
      similar products.

      Many healthcare  companies are offering  disease  management  services and
healthcare focused software solutions.  Further, a vast number of Internet sites
offer  healthcare  content,  products and  services.  In  addition,  traditional
healthcare  providers compete for consumers'  attention both through traditional
means as well as through  new  Internet  initiatives.  Although  we believe  our
technology-enabled   service   solutions   are  unique   and  better   than  our
competitors', we compete for customers with numerous other businesses.

         Many of these potential competitors are likely to enjoy substantial
competitive advantages compared to us, including:

      o     greater name recognition and larger marketing budgets and resources;

      o     larger customer and user bases;



                                      -9-



      o     larger production and technical staffs;

      o     substantially greater financial, technical and other resources; and

      o     a wider array of online products and services.

         To be competitive, we must continue to enhance our products and
services, as well as our sales and marketing channels and our financial
condition.

         We may be exposed to liability claims.

      We maintain  professional  malpractice,  errors and  omissions and general
liability insurance for all of our locations and operations. Although we believe
that these  insurance  policies  are  adequate  in amount and  coverage  for our
current  operations,  there can be no assurance  that  coverage is sufficient to
cover all future claims or will continue to be available in adequate  amounts or
at a reasonable cost.

      I-trax Health Management Solutions,  Inc., our operating  subsidiary,  had
engaged in the physician practice  management  business.  While we are no longer
engaged  in  that  business,   Health  Management  may  be  subject  to  unknown
liabilities  arising  from  such  prior  business  operations,  which may have a
material adverse effect on our business,  operations,  financial  condition,  or
prospects.

      Member-Link  Systems,  Inc.,  a company  we  acquired  in 1999 by way of a
merger with Health Management, was engaged in the business of marketing, selling
and installing eImmune(R) and AsthmaWatch(R)  applications.  Since beginning its
operations in 1996 until March 15, 2000,  Member-Link and Health  Management did
so without obtaining product or professional  liability insurance.  Accordingly,
if any customer of Member-Link or Health  Management  should in the future claim
that the software  applications  Member-Link and Health Management sold prior to
obtaining  insurance  on March 15,  2000 were  defective,  we would not have the
protection of insurance in satisfying or defending  against such claims. At this
time we are not aware of any such claims. Any such claims, however, could have a
material  adverse  effect on our  business,  results  of  operations,  financial
condition and prospects.

      Our clients may sue us if any of our software  applications or services is
defective,  fails to  perform  properly  or  injures  the user.  Even  though we
currently have insurance,  claims could require us to spend significant time and
money  in  litigation,  to pay  significant  damages  and to  reserve  for  such
liability on our financial statements. At this time we are not aware of any such
claims.  However,  any such claims,  whether or not successful,  could seriously
damage our  reputation  and our  business,  results of  operations  or financial
position.

      If our intellectual  property rights are undermined by third parties,  our
      business will suffer.

      Our  intellectual  property is  important  to our  business.  We rely on a
combination  of  copyright,  trademark  and trade secret  laws,  confidentiality
procedures and contractual  provisions to protect our intellectual property. Our
efforts  to  protect  our  intellectual  property  may  not  be  adequate.   Our
competitors  may  independently  develop  similar  technology  or duplicate  our
products or services.  Unauthorized  parties may infringe upon or misappropriate
our products, services or proprietary information. In addition, the laws of some
foreign countries do not protect  proprietary  rights as well as the laws of the
United  States do, and the global  nature of the Internet  makes it difficult to
control the ultimate  destination  of our products and services.  In the future,
litigation may be necessary to enforce our  intellectual  property  rights or to
determine the validity and scope of the proprietary  rights of others.  Any such
litigation would probably be  time-consuming  and costly. We could be subject to
intellectual property infringement claims as the number of our competitors grows
and the content and functionality of software  applications and services overlap
with  competitive  offerings.  Defending  against  these  claims,  even  if  not
meritorious,  could be expensive  and divert our  attention  from  operating our
company.  If we become liable to third parties for infringing their intellectual
property  rights,  we could be required to pay a  substantial  damage  award and
forced to develop  noninfringing  technology,  obtain a license or cease selling
the  applications  that contain the infringing  technology.  We may be unable to
develop noninfringing  technology or obtain a license on commercially reasonable
terms,  or at all. We also intend to rely on a variety of  technologies  that we
will  license from third  parties,  including  any database and Internet  server
software,  which will be used to operate  our  applications.  These  third-party
licenses


                                      -10-



may not be  available to us on  commercially  reasonable  terms.  The loss of or
inability  to  obtain  and  maintain  any of  these  licenses  could  delay  the
introduction of enhancements to our software applications, interactive tools and
other features until equivalent  technology could be licensed or developed.  Any
such  delays  could  materially  adversely  affect  our  business,   results  of
operations and financial condition.

      Provisions of our certificate of incorporation  could impede a takeover of
      our company even though a takeover may benefit our stockholders.

      Our board of directors has the  authority,  without  further action by the
stockholders,  to issue from time to time,  up to 2,000,000  shares of preferred
stock in one or more classes or series, and to fix the rights and preferences of
such  preferred  stock.  We are subject to provisions of Delaware  corporate law
which,  subject to certain  exceptions,  will  prohibit us from  engaging in any
"business   combination"  with  a  person  who,  together  with  affiliates  and
associates,  owns 15% or more of our common stock  (referred to as an interested
stockholder)  for a period of three  years  following  the date that such person
became an interested stockholder, unless the business combination is approved in
a  prescribed  manner.  Additionally,  our bylaws  establish  an advance  notice
procedure for stockholder  proposals and for nominating  candidates for election
as  directors.  These  provisions  of  Delaware  law and of our  certificate  of
incorporation  and  bylaws  may  have  the  effect  of  delaying,  deterring  or
preventing a change in our control,  may discourage bids for our common stock at
a premium over market price and may adversely  affect the market price,  and the
voting and other rights of the holders of our common stock.

      Our officers and directors have effective control of the company and other
      stockholders may have little or no voice in corporate management.

      Our  Chairman,  the  venture  capital  firm  with  which our  Chairman  is
affiliated,  three  other  members  of our  management  team  and two  directors
beneficially own, in the aggregate,  approximately 30% of the outstanding shares
of  our  common  stock.  As  a  result,  these  stockholders,  acting  together,
effectively  control the election of directors and matters requiring approval by
our stockholders.  Thus, they may be able to prevent corporate transactions such
as future  mergers that might be favorable from our standpoint or the standpoint
of the other stockholders.

      The  loss of any of our very  limited  number  of  customers  will  have a
      material adverse effect on our business.

      Historically,  a very limited  number of  customers  has  accounted  for a
significant  percentage of our revenues.  In 2001, our largest customer,  Walter
Reed Army  Medical  Center,  accounted  for 84% of our  revenues.  In 2002,  our
largest customers, UICI and Aetna Health Management,  Inc. accounted for 42% and
30% of our revenues,  respectively. We anticipate that our results of operations
in any given period will continue to depend to a significant extent upon a small
number of  customers.  Accordingly,  if we were to lose the  business  of even a
single  customer,  our results of operations  would be materially  and adversely
affected.

      If we  cannot  repay  the  debenture  we sold to  Palladin,  we will be in
      default  on a  material  obligation,  which  will  cause us to suffer a
      material adverse event.

      We owe Palladin  Opportunity Fund, LLC (or Palladin) $2,000,000 under a 6%
convertible  senior  debenture.  If Palladin  does not convert this sum into our
common stock,  this sum,  together with interest,  must be repaid on February 3,
2004. If we do not have  sufficient  funds to repay this sum on debenture's  due
date,  we will be in  default  on a  material  obligation  and as a  result  our
operations may be materially and adversely effected.

Investment Risks

      The price of our common stock is volatile.

      Our stock price has been and we believe will continue to be volatile.  For
example, in 2002, the per share price of our stock has fluctuated from a high of
$7.65  to a low of  $2.50.  The  stock's  volatility  may be  influenced  by the
market's  perceptions of the healthcare  sector in general,  or other  companies
believed to be similar to us or by the market's perception of our operations and
future prospects. Many of these perceptions are beyond our control. In


                                      -11-



addition,  our stock is not heavily  traded and therefore the ability to achieve
relatively  quick  liquidity  without a  negative  impact on our stock  price is
limited.

         Shares  eligible  for future sale upon the  conversion  of the
         debenture  and upon the exercise of issued options and warrants may
         cause significant dilution.

      Palladin  purchased  from us a  debenture  with the  principal  amount  of
$2,000,000.  The debenture and accrued  interest on the debenture is convertible
into such number of shares of our common  stock as  determined  by dividing  the
principal  amount and accrued  interest  thereon by the then current  conversion
price.  If  converted  on June  30,  2003,  the  debenture  would  convert  into
approximately 1,240,960 shares of our common stock. Our stockholders, therefore,
could experience  dilution of their investment upon conversion of the debenture.
The shares of common stock  issuable  upon the  conversion  of the debenture are
registered under the Securities Act of 1933, as amended (or Securities Act), and
may be sold by Palladin, subject to certain limitations, at any time.

      As of June 30, 2003,  approximately  5,489,092  shares of our common stock
were reserved for issuance upon exercise of our outstanding warrants and options
in addition to the shares of our common stock  reserved  for  issuance  upon the
conversion of the debenture.

         We may need  additional  funds in the  future  which may not be
         available  and which may result in dilution of the value of our common
         stock

      In the future,  we may need to raise  additional  funds,  which may not be
available on favorable  terms, if at all. If adequate funds are not available on
acceptable  terms,  we may be  unable  to fund our  business  growth  plans.  In
addition,  if funds are available,  the issuance of securities  could dilute the
value of shares of our common stock and cause the market price to fall.



                                      -12-




                           MARKET FOR OUR COMMON STOCK

      Our common stock trades on the American  Stock  Exchange  under the symbol
"DMX."   Prior  to  January   15,   2003,   our  common   stock  was  quoted  on
Over-the-Counter  Bulletin  Board  under  the  symbol  "IMTX"  and  "ITRX."  The
following  table sets forth the high and low closing prices for our common stock
for the periods  indicated.  All closing  prices have been adjusted to reflect a
1-for-5 reverse stock split effected as of close of business on January 3, 2003.





                                                                                          
                                                                                High                    Low
                                                                              --------                --------
         2003
              Third Quarter (through August 20, 2003)                         $  3.790                $  2.850
              Second Quarter                                                     3.000                   1.510
              First Quarter                                                      5.000                   1.370

         2002
              Fourth Quarter                                                     4.300                   2.500
              Third Quarter                                                      5.100                   2.750
              Second Quarter                                                     6.625                   4.150
              First Quarter                                                      7.650                   5.100

         2001
              Fourth Quarter                                                     8.350                   1.800
              Third Quarter                                                      3.850                   1.800
              Second Quarter                                                     5.155                   2.900
              First Quarter                                                     15.000                   3.440




      We obtained the information presented above from Nasdaq.com.

      As of August 20, 2003, there were  approximately 465 registered holders of
our common  stock.  On August 20,  2003,  the last  reported  sales price of our
common stock was $2.80.

Dividend Policy

      We have never paid or declared  any cash  dividends on our common stock or
other securities and do not anticipate  paying cash dividends in the foreseeable
future.

                                 USE OF PROCEEDS

      We will not  receive  any  proceeds  from the sale of shares of our common
stock offered under this prospectus.  However,  we may receive proceeds from the
exercise of the warrants by the selling  shareholders,  which  proceeds  will be
used for general corporate purposes.




                                      -13-




                            SELLING SECURITY HOLDERS

         We are registering for offer and sale by the applicable holders:

      o     up to 1,218,628 shares of our common stock; and

      o     up to 416,667  shares of common stock  issuable upon the exercise of
            outstanding  warrants and  conversion  of a  convertible  promissory
            note.

      The selling  shareholders  may offer their shares for sale on a continuous
basis pursuant to Rule 415 under the Securities Act.

      None of the selling  shareholders and their principals has held a position
or office, or has any other material  relationship,  with us, except as follows.
From February 2001 through May 2002,  Hans C.  Kastensmith  served as a director
and Vice  Chairman  of  I-trax.  The Del Mar  Consulting  Group,  Inc.,  Michael
Steinberg and Barry Honig provide consulting services to I-trax.  Robert Prag is
a principal of The Del Mar Consulting  Group, Inc. Barry Honig is an employee of
Marlins Capital, LLC.

      All of the selling  shareholders'  shares covered by this  prospectus will
become  tradable  upon  conversion  on the  effective  date of the  registration
statement of which this prospectus is a part.

      Based on  information  provided  to us by the  selling  shareholders,  the
following table sets forth ownership and registration  information regarding the
shares held by the selling shareholders.







                                                                                     Common Stock Owned After
                                                     Number of                         Offering Is Complete
Name of Selling Shareholder                          Shares of        Number of
                                                   Common Stock       Shares of
                                                   Owned Before      Common Stock    Number of
                                                   Offering (1)        Offered       Shares        Percentage
------------------------------------------------- ---------------- ----------------- -------------- ----------------
                                                                                   
Hans C. Kastensmith                                       489,520           420,114         69,406
The Del Mar Consulting Group, Inc.                        490,000           464,051         25,949
Joseph and Greta Shamy, JT (2)                            578,630           338,630        240,000       2.2%
Michael Steinberg (3)                                     125,000           125,000             --
Barry Honig (3)                                           125,000           125,000             --
Robert Prag                                                43,000            43,000             --
Marlins Capital, LLC                                       33,000            33,000             --
Andrew Friis                                               33,000            33,000             --
Charles O. Howey Trust                                     20,000            20,000             --
Evan Taber                                                 12,500            12,500             --
Marco Palatini                                              8,000             8,000             --
Marc Rubin                                                  5,000             5,000             --
Mento Soponis                                               4,000             4,000             --
Leo C. Mueller, III                                         2,000             2,000             --
Leo C. Mueller, JR                                          2,000             2,000             --
                                                  ---------------- ----------------- --------------

                                          TOTAL:        1,970,650         1,635,295        335,355





      (1)   The  actual  number  of  shares  of  common  stock  offered  in this
            prospectus, and included in the registration statement of which this
            prospectus is a part,  includes such additional  number of shares of
            common  stock as may be  issued or  issuable  by reason of any stock
            split,  stock dividend or similar  transaction  involving the common
            stock, in accordance with Rule 416 under the Securities Act.

      (2)   The  aggregate  number of shares  offered  include  66,667 shares of
            common stock  issuable  upon the  conversion at $1.50 per share of a
            convertible  promissory note in the principal amount of


                                      -14-




             $100,000  and  100,000  share of  common  stock  issuable  upon the
             exercise of a warrant at $1.50 per share.

      (3)   The offered  shares are  issuable  upon the exercise of a warrant at
            $1.50 per share.


                              PLAN OF DISTRIBUTION

      The shares being offered by the selling  shareholders or their  respective
pledgees, donees, transferees or other successors in interest, will be sold from
time to time in one or more transactions, which may involve block transactions:

      o     on the American  Stock Exchange or on such other market on which the
            common stock may from time to time be trading;

      o     in privately-negotiated transactions;

      o     through the writing of options on the shares;

      o     short sales; or

      o     any combination thereof.

     The sale price to the public may be:

      o     the market price prevailing at the time of sale;

      o     a price related to such prevailing market price;

      o     at negotiated prices; or

      o     such other price as the selling shareholders  determine from time to
            time.

      The shares may also be sold pursuant to Rule 144. The selling shareholders
shall have the sole and absolute  discretion not to accept any purchase offer or
make any sale of shares if they deem the purchase price to be  unsatisfactory at
any particular time.

      The selling shareholders or their respective pledgees, donees, transferees
or other  successors  in interest,  may also sell the shares  directly to market
makers acting as principals or broker-dealers acting as agents for themselves or
their  customers.  These  broker-dealers  may  be  compensated  with  discounts,
concessions or commissions  from the selling  shareholders  or the purchasers of
shares  for whom such  broker-dealers  may act as agents or to whom they sell as
principal or both. The  compensation as to a particular  broker-dealer  might be
greater  than  customary   commissions.   Market  makers  and  block  purchasers
purchasing  the shares  will do so for their own  account and at their own risk.
The selling  shareholders may sell shares of common stock in block  transactions
to market makers or other  purchasers  at a price per share,  which may be below
the then market price. The selling shareholders cannot assure that all or any of
the shares offered in this prospectus will be issued to, or sold by, the selling
shareholders.  The selling shareholders and any brokers, dealers or agents, upon
effecting  the sale of any of the  shares  offered  in this  prospectus,  may be
deemed  "underwriters"  as that term is defined under the  Securities Act or the
Securities  Exchange Act of 1934 (or Exchange Act) or the rules and  regulations
under such acts.

      The selling shareholders,  alternatively,  may sell all or any part of the
shares offered in this prospectus through an underwriter. No selling stockholder
has entered into any agreement  with a prospective  underwriter  and there is no
assurance   that  any  such  agreement  will  be  entered  into.  If  a  selling
shareholders  enters into such an agreement or agreements,  the relevant details
will be set forth in a supplement or revisions to this prospectus.


                                      -15-



      The selling  shareholders and any other persons  participating in the sale
or  distribution  of the shares will be subject to applicable  provisions of the
Exchange Act and the rules and  regulations  under the Exchange Act,  including,
without  limitation,   Regulation  M.  These  provisions  may  restrict  certain
activities  of, and limit the timing of purchases and sales of any of the shares
by, the  selling  shareholders  or any other  such  person.  Furthermore,  under
Regulation M, persons  engaged in a  distribution  of securities  are prohibited
from simultaneously  engaging in market making and certain other activities with
respect  to  such  securities  for a  specified  period  of  time  prior  to the
commencement  of  such  distributions,   subject  to  specified   exceptions  or
exemptions. All of these limitations may affect the marketability of the shares.


                              AVAILABLE INFORMATION

      We file reports, proxy statements and other information with the SEC (File
No. 0-30275).  Copies of these reports,  proxy statements and other  information
may be inspected and copied at the public reference facilities maintained by the
SEC at Judiciary  Plaza,  Room 1024, 450 Fifth Street,  N.W.,  Washington,  D.C.
20549.

      Copies of these materials can also be obtained by mail at prescribed rates
from  the  Public  Reference  Section  of  the  SEC,  450  Fifth  Street,  N.W.,
Washington,  D.C.  20549  or by  calling  the  SEC at  1-800-SEC-0330.  The  SEC
maintains  a  website  that  contains   reports,   proxy  statements  and  other
information   regarding   our   company.   The   address  of  this   website  is
http://www.sec.gov.

      We have filed a  registration  statement on Form S-3 under the  Securities
Act with the SEC with respect to the shares of our common stock  covered by this
prospectus.  This document constitutes the prospectus of I-trax filed as part of
that  registration  statement.  This  document  does  not  contain  all  of  the
information set forth in the  registration  statement  because some parts of the
registration  statement are omitted as provided by the rules and  regulations of
the SEC.  You may  inspect  and copy the  registration  statement  at any of the
addresses listed above.


                 INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

      The  following  documents  we have filed  with the SEC (File No.  0-30275)
pursuant to the Exchange Act are incorporated herein by reference:

      o     our Annual  Report on Form  10-KSB for the year ended  December  31,
            2002, filed on April 15, 2003,

      o     our amended  Quarterly Reports on Form 10-QSB for the quarters ended
            March 31, 2002,  June 30, 2002 and September 30, 2002, each filed on
            May 15, 2003,

      o     our Quarterly Reports on Form 10-QSB for the quarter ended March 31,
            2003, filed on May 15, 2003, and our Quarterly Report on Form 10-QSB
            for the quarter ended June 30, 2003, filed on August 14, 2003,

      o     our Current Reports on Form 8-K filed on February 12, 2003, February
            19, 2003, April 22, 2003, May 19, 2003 and August 15, 2003,

      o     the description of our common stock,  $0.01 par value per share, and
            associated rights,  contained in our registration  statement on Form
            8-A,  filed on January 14, 2003,  including  any amendment or report
            filed for the purpose of updating this description, and

      o     all  reports  and other  documents  filed by us pursuant to Sections
            13(a), 13(c), 14 or 15(d) of the Exchange Act subsequent to the date
            of this prospectus and prior to the termination of the offering.

      Any statement  contained in a document  incorporated  by reference in this
prospectus will be deemed to be incorporated by reference in this prospectus and
to be part of this  prospectus  from the date of  filing  of the  document.  Any
statement  modified or superseded  will not be deemed,  except as so modified or
superseded,  to  constitute  a part


                                      -16-



of this prospectus.  We will provide upon written or oral request without charge
to each person to whom this  prospectus is delivered a copy of any or all of the
documents which are  incorporated  in this  prospectus by reference  (other than
exhibits to those documents unless those exhibits are specifically  incorporated
by reference  into the documents  that this  prospectus  incorporates).  Written
requests for copies should be directed to I-trax, Inc., Investor Relations,  One
Logan Square, Suite 2615, 130 N. 18th Street, Philadelphia,  Pennsylvania 19103.
Our telephone number is (215) 557-7488.


                                  LEGAL MATTERS

      The validity of the shares of our common stock offered by this  prospectus
will be passed upon for us by our Vice President, General Counsel and Secretary.


                                     EXPERTS

      The financial  statements  incorporated in this prospectus by reference to
the Annual Report on Form 10-KSB of I-trax, Inc. for the year ended December 31,
2002 have been so  incorporated  in reliance on the reports of  Goldstein  Golub
Kessler LLP,  independent  accountants,  given on the  authority of said firm as
experts in auditing and accounting

      The financial  statements  incorporated in this prospectus by reference to
the Annual Report on Form 10-KSB of I-trax, Inc. for the year ended December 31,
2001   have   been   so   incorporated   in   reliance   on   the   reports   of
PricewaterhouseCoopers  LLP, independent accountants,  given on the authority of
said firm as experts in auditing and accounting.




                                      -17-




PART II  INFORMATION NOT REQUIRED IN PROSPECTUS

ITEM 14. OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION

         The following table sets forth the costs and expenses payable by I-trax
in connection with the sale of the securities being registered. All amounts are
estimates except the SEC registration fee:

        SEC registration fee                                         $  $373
        Printing and engraving expenses                                1,000
        Accounting fees and expenses                                   6,000
        Attorneys' fees and expenses                                   2,000
        Transfer agent's fees and expenses                             1,000
        Miscellaneous                                                    627

                 Total:                                            $  11,000



ITEM 15. INDEMNIFICATION OF OFFICERS AND DIRECTORS

      Section  145(a) of the Delaware  General  Corporation  Law provides that a
Delaware  corporation  may  indemnify  any  person  who was or is a party  or is
threatened to be made a party to any  threatened,  pending or completed  action,
suit or proceeding,  whether civil,  criminal,  administrative or investigative,
other  than an action by or in the  right of the  corporation,  by reason of the
fact that he is or was a director, officer, employee or agent of the corporation
or is or was serving at the request of the  corporation as a director,  officer,
employee  or agent of  another  corporation  or  enterprise,  against  expenses,
judgments, fines and amounts paid in settlement actually and reasonably incurred
by him in  connection  with such action,  suit or proceeding if he acted in good
faith and in a manner he reasonably believed to be in or not opposed to the best
interests  of the  corporation  and,  with  respect  to any  criminal  action or
proceeding, had no cause to believe his conduct was unlawful.

      Section  145(b) of the Delaware  General  Corporation  Law provides that a
Delaware  corporation  may  indemnify  any  person  who was or is a party  or is
threatened to be made a party to any threatened,  pending or completed action or
suit by or in the right of the corporation to procure a judgment in its favor by
reason of the fact that such  person  acted in any of the  capacities  set forth
above,  against expenses  actually and reasonably  incurred by him in connection
with the defense or  settlement of such action or suit if he acted in good faith
and in a manner  he  reasonably  believed  to be in or not  opposed  to the best
interests  of the  corporation,  except that no  indemnification  may be made in
respect of any claim,  issue or matter as to which such  person  shall have been
adjudged to be liable to the corporation  unless and only to the extent that the
court in which such action or suit was brought  shall  determine  that,  despite
such adjudication of liability, such person is fairly and reasonably entitled to
be indemnified for such expenses which the court shall deem proper.

      Section 145 of the Delaware General  Corporation Law further provides that
to the  extent  a  director  or  officer  of a  Delaware  corporation  has  been
successful  in the  defense of any  action,  suit or  proceeding  referred to in
subsections  (a) or (b) of Section 145 or in the defense of any claim,  issue or
matter  therein,  he shall be  indemnified  against any  expenses  actually  and
reasonably  incurred by him in connection  therewith;  that the  indemnification
provided for by Section 145 shall not be deemed exclusive of any rights to which
the  indemnified  party may be entitled  and the  corporation  may  purchase and
maintain insurance on behalf of a director or officer of the corporation against
any  liability  asserted  against him or incurred by him in any such capacity or
arising out of his status as such whether or not the corporation  would have the
power to indemnify him against such liabilities under Section 145.

      Section  102(b)(7)  of the  Delaware  General  Corporation  Law  permits a
Delaware corporation to include a provision in its Certificate of Incorporation,
and I-trax's  Certificate  of  Incorporation  contains such a provision,  to the

                                     -II-1-





effect that, subject to certain exceptions, a director of a Delaware corporation
is not personally  liable to the  corporation or its  stockholders  for monetary
damages for a breach of his fiduciary duty as a director.

      I-trax's  By-laws also provide that I-trax shall  indemnify  its directors
and officers and, to the extent  permitted by the Board of  Directors,  I-trax's
employees  and  agents,  to the  full  extent  permitted  by  and in the  manner
permissible  under  the laws of the State of  Delaware.  In  addition,  I-trax's
By-laws  permit the Board of Directors to authorize  the Company to purchase and
maintain  insurance against any liability  asserted against any of the Company's
directors, officers, employees or agents arising out of their capacity as such.

ITEM 16. EXHIBITS

      NUMBER            EXHIBIT TITLE
      ------            -------------

          5*        Opinion of Vice President, General Counsel and Secretary.

          23.1*     Consent of Vice  President,  General  Counsel and Secretary.
                    (Included in Exhibit 5.)

          23.2*     Consent of Goldstein Golub Kessler LLP.

          23.3*     Consent of PricewaterhouseCoopers LLP.

          24        Power of Attorney. (Included in signature page.)

      _____________________________
          *         Filed with this registration statement.

ITEM 17.          UNDERTAKINGS

         The undersigned registrant hereby undertakes to:

      (1) File,  during  any  period in which it offers or sells  securities,  a
post-effective   amendment  to  this  registration   statement  to  include  any
additional or changed material information on the plan of distribution.

      (2) For  determining  liability  under  the  Securities  Act,  treat  each
post-effective  amendment  as a new  registration  statement  of the  securities
offered,  and the offering of the securities at that time to be the initial bona
fide offering.

      (3) File a post-effective amendment to remove from registration any of the
securities that remain unsold at the end of the offering.

      Insofar as  indemnification  for liabilities  arising under the Securities
Act of 1933 may be permitted to directors,  officers and controlling  persons of
the small business  issuer pursuant to the foregoing  provisions,  or otherwise,
the small business issuer has been advised that in the opinion of the Securities
and  Exchange  Commission  such  indemnification  is  against  public  policy as
expressed in the Act and is, therefore, unenforceable. In the event that a claim
for  indemnification  against  such  liabilities  (other than the payment by the
small  business  issuer of expenses  incurred or paid by a director,  officer or
controlling person of the small business issuer in the successful defense of any
action, suit or proceeding) is asserted by such director, officer or controlling
person in connection with the securities  being  registered,  the small business
issuer will, unless in the opinion of its counsel the matter has been settled by
controlling  precedent,  submit  to a  court  of  appropriate  jurisdiction  the
question  whether  such  indemnification  by  it is  against  public  policy  as
expressed in the Securities  Act and will be governed by the final  adjudication
of such issue.


                                     -11-2-




                                   SIGNATURES

      Pursuant to the requirements of the Securities Act of 1933, the registrant
certifies  that it has  reasonable  grounds to believe  that it meets all of the
requirements of filing of this  Registration  Statement on Form S-3 and has duly
caused  this  registration   statement  to  be  singed  on  its  behalf  by  the
undersigned, thereunto duly authorized in the City of Philadelphia, Commonwealth
of Pennsylvania on August 22, 2003.

                         I-TRAX, INC.

                         By:      /s/ Frank A. Martin
                                  -----------------------------
                                  Frank A. Martin, Chairman and
                                  Chief Executive Officer

                         By:      /s/ William S. Wheeler
                                  ----------------------------------------------
                                  William S. Wheeler,  Chief  Financial Officer
                                  (Principal  Financial and  Accounting Officer)

      In accordance  with the  requirements  of the Securities Act of 1933, this
Registration  Statement on Form S-3 was signed by the  following  persons in the
capacities and on the dates stated.

      Each  person  whose  signature  appears  below in so signing  also  makes,
constitutes  and  appoints  Frank A. Martin and  William S.  Wheeler and each of
them,  his  or  her  true  and  lawful  attorney-in-fact,  with  full  power  of
substitution,  for him or her in any and all capacities, to execute and cause to
be filed with the Securities and Exchange  Commission any and all amendments and
post-effective  amendments  to  this  Registration  Statement  and  any  related
registration statement (and any and all amendments and post-effective amendments
thereto)  contemplated by Rule 462 under the Securities Act of 1933, as amended,
in each case with exhibits  thereto and other documents in connection  therewith
and hereby  ratifies and confirms all that said  attorney-in-fact  or his or her
substitute or substitutes may do or cause to be done by virtue hereof.




Signature                          Title                                  Date
-----------------------            ---------------------------------      ---------------

                                                                               
/s/ Frank A. Martin                Chairman, Chief Executive Officer,     August 22, 2003
-----------------------            President and Director
Frank A. Martin

/s/ Carol Rehtmeyer                Director                               August 22, 2003
-----------------------
Carol Rehtmeyer

/s/ John Blazek                    Director                               August 22, 2003
-----------------------
John Blazek

/s/ David R. Bock                  Director                               August 22, 2003
-----------------------
David R. Bock

/s/ Philip D. Green                Director                               August 22, 2003
-----------------------
Philip D. Green


                                     -II-3-




/s/ Michael M.E. Johns             Director                               August 22, 2003
-----------------------
Dr. Michael M.E. Johns

/s/ Arthur N. Leibowitz            Director                               August 22, 2003
-----------------------
Dr. Arthur N. Leibowitz

/s/ David Nash                     Director                               August 22, 2003
-----------------------
Dr. David Nash

/s/ John R. Palumbo                Director                               August 22, 2003
-----------------------
John R. Palumbo

/s/ R. Dixon Thayer                Director                               August 22, 2003
-----------------------
R. Dixon Thayer

/s/ William S. Wheeler             Director                               August 22, 2003
-----------------------
William S. Wheeler



                                     -II-4-