1. Title of Derivative Security (Instr. 4) |
2. Date Exercisable and Expiration Date (Month/Day/Year) |
3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) |
4. Conversion or Exercise Price of Derivative Security |
5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5) |
6. Nature of Indirect Beneficial Ownership (Instr. 5) |
Date Exercisable |
Expiration Date |
Title |
Amount or Number of Shares |
Series A Preferred Stock
|
06/27/2006 |
Â
(1)
|
Common Stock
|
1,945,920
|
$
(1)
|
I
|
By Sequel Limited Partnership III
(2)
|
Series A Preferred Stock
|
06/27/2006 |
Â
(1)
|
Common Stock
|
54,080
|
$
(1)
|
I
|
By Sequel Entrepreneurs' Fund III, L.P.
(2)
|
SeriesC Preferred Stock
|
06/27/2006 |
Â
(1)
|
Common Stock
|
3,113,472
|
$
(1)
|
I
|
By Sequel Limited Partnership III
(2)
|
Series C Preferred Stock
|
06/27/2006 |
Â
(1)
|
Common Stock
|
86,528
|
$
(1)
|
I
|
By Sequel Entrepreneurs' Fund III, L.P.
(2)
|
Series D Preferred Stock
|
06/27/2006 |
Â
(1)
|
Common Stock
|
1,128,824
|
$
(1)
|
I
|
By Sequel Limited Partnership III
(2)
|
Series D Preferred Stock
|
06/27/2006 |
Â
(1)
|
Common Stock
|
31,372
|
$
(1)
|
I
|
By Sequel Entrepreneurs' Fund III, L.P.
(2)
|
Warrant (right to buy)
|
06/27/2006 |
06/27/2011 |
Series C Preferred Stock
|
38,919
(3)
|
$
1.25
(3)
|
I
|
By Sequel Limited Partnership III
(2)
|
Warrant (right to buy)
|
06/27/2006 |
06/27/2011 |
Series C Preferred Stock
|
1,083
(3)
|
$
1.25
(3)
|
I
|
By Sequel Entrepreneurs' Fund III, L.P.
(2)
|
* |
If the form is filed by more than one reporting person, see Instruction 5(b)(v). |
** |
Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). |
(1) |
The Issuer's preferred stock will automatically be converted into Common Stock upon the closing of the Issuer's initial public offering. The number of shares does not reflect the automatic conversion of each share of Series A, C and D Preferred Stock into 0.20391517 shares of Common Stock upon the closing of the initial public offering. |
(2) |
The Reporting Person is a manager of Sequel Venture Partners III, L.L.C., the general partner of Sequel Limited Partnership III and Sequel Entrepreneurs' Fund III, L.P. As such, the Reporting Person shares voting and investment power over the shares held by Sequel Limited Partnership III and Sequel Entrepreneurs' Fund III, L.P. and may be deemed to have indirect beneficial ownership of such shares. The Reporting Person disclaims beneficial ownership of such shares held by Sequel Limited Partnership III and Sequel Entrepreneurs' Fund III, L.P. except to his proportionate pecuniary interest therein. |
(3) |
The warrants to purchase shares of Series C Preferred Stock will automatically be converted into warrants to purchase shares of Common Stock upon the closing of the Issuer's initial public offering. The number of shares and exercise price do not reflect the automatic conversion of each share of Series C Preferred Stock into 0.20391517 shares of Common Stock upon the closing of the initial public offering. |