SECURITIES & EXCHANGE COMMISSION
                             Washington, D.C. 20549
                             ----------------------

                                  SCHEDULE 13G*
                                 (Rule 13d-102)

             INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
           TO RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED
                              PURSUANT TO 13d-2(b)


                               PROTOKINETIX, INC.
                                (Name of Issuer)

                       Common Stock, $0.0000053 par value
                         (Title of Class of Securities)

                                    743722100
                                 (CUSIP Number)

                                  July 7, 2006
             (Date of event which requires filing of this statement)


     Check the appropriate box to designate the rule pursuant to which this
Schedule 13G is filed:
     [ ]  Rule 13d-1(b)
     [X]  Rule 13d-1(c)
     [ ]  Rule 13d-1(d)





                               Page 1 of 11 Pages
----------------
     *The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter the disclosures provided in a prior cover page.

     The information required in the remainder of this cover page shall not be
deemed to be "filed" for purposes of Section 18 of the Securities Exchange Act
of 1934 ("Act") or otherwise subject to the liabilities of that section of the
Act but shall be subject to all other provisions of the Act (however, see the
Notes).






CUSIP No. 743722100                13G                    Page 2 of 11 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS
            I.R.S. IDENTIFICATION NO.
            OF ABOVE PERSONS (ENTITIES ONLY)
                                           Empire Capital Partners, L.P.
-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
                                                                  (a)  [ ]
                                                                  (b)  [X]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    CITIZENSHIP OR PLACE OF ORGANIZATION
                            Delaware
-----------------------------------------------------------------------------
NUMBER OF      (5)  SOLE VOTING POWER
                                                -0-
SHARES         ______________________________________________________________

BENEFICIALLY   (6)  SHARED VOTING POWER
                                                1,082,933
OWNED BY       ______________________________________________________________

EACH           (7)  SOLE DISPOSITIVE POWER
                                                -0-
REPORTING      ______________________________________________________________

PERSON WITH    (8)  SHARED DISPOSITIVE POWER
                                                1,082,933
-----------------------------------------------------------------------------
     (9)    AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
                                                1,082,933
-----------------------------------------------------------------------------
     (10)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (9) EXCLUDES CERTAIN SHARES **                       [ ]
-----------------------------------------------------------------------------
     (11)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (9)
                                                2.6%
-----------------------------------------------------------------------------
     (12)   TYPE OF REPORTING PERSON **
                                                PN
-----------------------------------------------------------------------------
                     ** SEE INSTRUCTIONS BEFORE FILLING OUT!






CUSIP No. 743722100                13G                    Page 3 of 11 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS
            I.R.S. IDENTIFICATION NO.
            OF ABOVE PERSONS (ENTITIES ONLY)
                                           Empire GP, L.L.C.
-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
                                                                  (a)  [ ]
                                                                  (b)  [X]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    CITIZENSHIP OR PLACE OF ORGANIZATION
                            Delaware
-----------------------------------------------------------------------------
NUMBER OF      (5)  SOLE VOTING POWER
                                                -0-
SHARES         ______________________________________________________________

BENEFICIALLY   (6)  SHARED VOTING POWER
                                                1,082,933
OWNED BY       ______________________________________________________________

EACH           (7)  SOLE DISPOSITIVE POWER
                                                -0-
REPORTING      ______________________________________________________________

PERSON WITH    (8)  SHARED DISPOSITIVE POWER
                                                1,082,933
-----------------------------------------------------------------------------
     (9)    AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
                                                1,082,933
-----------------------------------------------------------------------------
     (10)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (9) EXCLUDES CERTAIN SHARES **                       [ ]
-----------------------------------------------------------------------------
     (11)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (9)
                                                2.6%
-----------------------------------------------------------------------------
     (12)   TYPE OF REPORTING PERSON **
                                                OO
-----------------------------------------------------------------------------
                     ** SEE INSTRUCTIONS BEFORE FILLING OUT!






CUSIP No. 743722100                13G                    Page 4 of 11 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS
            I.R.S. IDENTIFICATION NO.
            OF ABOVE PERSONS (ENTITIES ONLY)
                                           Empire Capital Management, L.L.C.
-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
                                                                  (a)  [ ]
                                                                  (b)  [X]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    CITIZENSHIP OR PLACE OF ORGANIZATION
                            Delaware
-----------------------------------------------------------------------------
NUMBER OF      (5)  SOLE VOTING POWER
                                                -0-
SHARES         ______________________________________________________________

BENEFICIALLY   (6)  SHARED VOTING POWER
                                                1,122,067
OWNED BY       ______________________________________________________________

EACH           (7)  SOLE DISPOSITIVE POWER
                                                -0-
REPORTING      ______________________________________________________________

PERSON WITH    (8)  SHARED DISPOSITIVE POWER
                                                1,122,067
-----------------------------------------------------------------------------
     (9)    AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
                                                1,122,067
-----------------------------------------------------------------------------
     (10)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (9) EXCLUDES CERTAIN SHARES **                       [ ]
-----------------------------------------------------------------------------
     (11)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (9)
                                                2.7%
-----------------------------------------------------------------------------
     (12)   TYPE OF REPORTING PERSON **
                                                OO
-----------------------------------------------------------------------------
                     ** SEE INSTRUCTIONS BEFORE FILLING OUT!






CUSIP No. 743722100                13G                    Page 5 of 11 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS
            I.R.S. IDENTIFICATION NO.
            OF ABOVE PERSONS (ENTITIES ONLY)
                                           Scott A. Fine
-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
                                                                  (a)  [ ]
                                                                  (b)  [X]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    CITIZENSHIP OR PLACE OF ORGANIZATION
                            United States
-----------------------------------------------------------------------------
NUMBER OF      (5)  SOLE VOTING POWER
                                                -0-
SHARES         ______________________________________________________________

BENEFICIALLY   (6)  SHARED VOTING POWER
                                                2,205,000
OWNED BY       ______________________________________________________________

EACH           (7)  SOLE DISPOSITIVE POWER
                                                -0-
REPORTING      ______________________________________________________________

PERSON WITH    (8)  SHARED DISPOSITIVE POWER
                                                2,205,000
-----------------------------------------------------------------------------
     (9)    AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
                                                2,205,000
-----------------------------------------------------------------------------
     (10)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (9) EXCLUDES CERTAIN SHARES **                       [ ]
-----------------------------------------------------------------------------
     (11)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (9)
                                                5.3%
-----------------------------------------------------------------------------
     (12)   TYPE OF REPORTING PERSON **
                                                IN
-----------------------------------------------------------------------------
                     ** SEE INSTRUCTIONS BEFORE FILLING OUT!






CUSIP No. 743722100                13G                    Page 6 of 11 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS
            I.R.S. IDENTIFICATION NO.
            OF ABOVE PERSONS (ENTITIES ONLY)
                                           Peter J. Richards
-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
                                                                  (a)  [ ]
                                                                  (b)  [X]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    CITIZENSHIP OR PLACE OF ORGANIZATION
                            United States
-----------------------------------------------------------------------------
NUMBER OF      (5)  SOLE VOTING POWER
                                                -0-
SHARES         ______________________________________________________________

BENEFICIALLY   (6)  SHARED VOTING POWER
                                                2,205,000
OWNED BY       ______________________________________________________________

EACH           (7)  SOLE DISPOSITIVE POWER
                                                -0-
REPORTING      ______________________________________________________________

PERSON WITH    (8)  SHARED DISPOSITIVE POWER
                                                2,205,000
-----------------------------------------------------------------------------
     (9)    AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
                                                2,205,000
-----------------------------------------------------------------------------
     (10)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (9) EXCLUDES CERTAIN SHARES **                       [ ]
-----------------------------------------------------------------------------
     (11)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (9)
                                                5.3%
-----------------------------------------------------------------------------
     (12)   TYPE OF REPORTING PERSON **
                                                IN
-----------------------------------------------------------------------------
                     ** SEE INSTRUCTIONS BEFORE FILLING OUT!






CUSIP No. 743722100                13G                    Page 7 of 11 Pages

Item 1(a).     Name of Issuer:

     The name of the issuer is PROTOKINETIX, INC. (the "Company").

Item 1(b).     Address of Issuer's Principal Executive Offices:

     The Company's principal executive offices are located at Suite 1500-885
West Georgia Street, Vancouver, British Columbia, Canada V6C3E

Item 2(a).     Name of Person Filing:

     This statement is filed by:
            (i)      Empire Capital Partners, L.P., a Delaware limited
                     partnership ("Empire Capital"), with respect to the
                     shares of Common Stock (as defined below) directly
                     owned by it;

            (ii)     Empire GP, L.L.C., a Delaware limited liability
                     company ("Empire GP"), with respect to the shares of
                     Common Stock directly owned by Empire Capital;

            (iii)    Empire Capital Management, L.L.C., a Delaware limited
                     liability company ("Empire Management") with respect
                     to the shares of Common Stock directly owned by
                     Empire Capital Partners, Ltd., Empire Capital
                     Partners II, Ltd. (the "Empire Overseas Funds"),
                     Charter Oak Partners, L.P. and Charter Oak Partners
                     II, L.P. (the "Charter Oak Funds")

            (iv)     Mr. Scott A. Fine ("Mr. Fine") with respect to the
                     shares of Common Stock directly owned by Empire
                     Capital, the Empire Overseas Funds and the Charter
                     Oak Funds; and

            (v)      Mr. Peter J. Richards ("Mr. Richards") with respect
                     to the shares of Common Stock directly owned by
                     Empire Capital, The Empire Overseas Funds and the
                     Charter Oak Funds.

                     The foregoing persons are hereinafter sometimes
            collectively referred to as the "Reporting Persons." Any
            disclosures herein with respect to persons other than the
            Reporting Persons are made on information and belief after
            making inquiry to the appropriate party.






CUSIP No. 743722100                13G                    Page 8 of 11 Pages

Item 2(c).     Citizenship:

       Empire Capital is a limited partnership organized under the laws of
       the State of Delaware. Empire GP and Empire Management are limited
       liability companies organized under the laws of the State of Delaware.
       Messrs. Fine and Richards are each a United States citizen.

Item 2(d).     Title of Class of Securities:

       Common Stock $0.0000053 par value (the "Common Stock")

Item 2(e).  CUSIP Number:   743722100



Item 3. If this statement is filed pursuant to Rules 13d-1(b) or 13d-2(b) or
(c), check whether the person filing is a:

          (a) [ ]  Broker or dealer registered under Section 15 of the
                   Act,

          (b) [ ]  Bank as defined in Section 3(a)(6) of the Act,

          (c) [ ]  Insurance Company as defined in Section 3(a)(19) of
                   the Act,

          (d) [ ]  Investment Company registered under Section 8 of the
                   Investment Company Act of 1940,

          (e) [ ]  Investment Adviser in accordance with Rule
                   13d-1 (b)(1)(ii)(E),

          (f) [ ]  Employee Benefit Plan or Endowment Fund in accordance
                   with 13d-1 (b)(1)(ii)(F),

          (g) [ ]  Parent Holding Company or control person in accordance
                   with Rule 13d-1 (b)(1)(ii)(G),

          (h) [ ]  Savings Association as defined in Section 3(b) of the
                   Federal Deposit Insurance Act,

          (i) [ ]  Church Plan that is excluded from the definition of an
                   investment company under Section 3(c)(14) of the
                   Investment Company Act of 1940,

          (j) [ ]  Group, in accordance with Rule 13d-1(b)(1)(ii)(J).

     If this statement is filed pursuant to 13d-1(c), check this box:  [x]






CUSIP No. 743722100                13G                    Page 9 of 11 Pages

Item 4.   Ownership.

      A. Empire Capital Partners, L.P. and Empire GP, L.L.C.
            (a) Amount beneficially owned: 1,082,933
            (b) Percent of class: 2.6%  The percentages used herein and in the
                rest of Item 4 are calculated based upon the 41,496,835 shares
                of Common Stock issued and outstanding as of May 8, 2006 as
                reflected in the Company's Form 10-QSB filed on May 22, 2006.
            (c)(i) Sole power to vote or direct the vote: -0-
              (ii) Shared power to vote or direct the vote: 1,082,933
             (iii) Sole power to dispose or direct the disposition: -0-
              (iv) Shared power to dispose or direct the
                   disposition: 1,082,933


Empire Capital has the power to dispose of and the power to vote the shares of
Common Stock beneficially owned by it, which power may be exercised by its
general partner, Empire GP. Empire GP does not directly own any shares of Common
Stock. By reason of the provisions of Rule 13d-3 of the Securities Exchange Act
of 1934 (the "Act"), Empire GP may be deemed to own beneficially the shares
owned by Empire Capital.

      B. Empire Management
            (a) Amount beneficially owned: 1,122,067
            (b) Percent of class: 2.7%
            (c)(i) Sole power to vote or direct the vote: -0-
              (ii) Shared power to vote or direct the vote: 1,122,067
             (iii) Sole power to dispose or direct the disposition: -0-
              (iv) Shared power to dispose or direct the disposition: 1,122,067

The Empire Overseas Funds have the power to dispose of and the power to vote the
shares of Common Stock beneficially owned by them, which power may be exercised
by their investment manager, Empire Management. Empire Management does not
directly own any shares of Common Stock. By reason of the provisions of Rule
13d-3 of the Securities Exchange Act of 1934 (the "Act"), Empire Management may
be deemed to own beneficially the shares owned by Empire Capital Offshore.

      C. Scott A. Fine and Peter J. Richards
            (a) Amount beneficially owned: 2,205,000
            (b) Percent of class: 5.3%
            (c)(i) Sole power to vote or direct the vote: -0-
              (ii) Shared power to vote or direct the vote: 2,205,000
             (iii) Sole power to dispose or direct the disposition: -0-
              (iv) Shared power to dispose or direct the disposition: 2,205,000

Messrs. Fine and Richards, as Members, direct the operations of Empire GP and
Empire Management. Neither Mr. Fine nor Mr. Richards directly own any shares of
Common Stock. By reason of the provisions of Rule 13d-3 of the Act, each may be
deemed to beneficially own the shares beneficially owned by Empire Capital, the
Empire Overseas Funds and the Charter Oak Funds.

Item 5.     Ownership of Five Percent or Less of a Class.

     Not applicable.






CUSIP No. 743722100                13G                    Page 10 of 11 Pages

Item 6.     Ownership of More than Five Percent on Behalf of Another Person.

     Empire GP, the general partner of Empire Capital, has the power to direct
the affairs of Empire Capital, including decisions respecting the disposition of
the proceeds from the sale of the Common Stock. Empire Management, the
investment manager of The Empire Overseas Funds has the power to direct the
affairs of the Empire Overseas Fund, including decisions respecting the
disposition of the proceeds from the sale of the Common Stock. Empire
Management, pursuant to investment management agreements with Charter Oak and
Charter Oak II, has the power to dispose of the proceeds from the sale of the
Common Stock with respect to those assets of the Charter Oak Funds under its
discretion. Messrs. Fine and Richards are the Members of Empire GP and Empire
Management, and in their capacities direct the operations of Empire GP and
Empire Management.

Item 7.     Identification and Classification of the Subsidiary Which Acquired
the Security Being Reported on by the Parent Holding Company.

     Not applicable.


Item 8.  Identification and Classification of Members of the Group.

     Not applicable.

Item 9.  Notice of Dissolution of Group.

     Not applicable.


Item 10.  Certification.

     Each of the Reporting Persons hereby makes the following certification:

By signing below I certify that, to the best of my knowledge and belief, the
securities referred to above were not acquired and are not held for the purpose
of or with the effect of changing or influencing the control of the issuer of
the securities and were not acquired and are not held in connection with or as a
participant in any transaction having that purpose or effect.






CUSIP No. 743722100                13G                    Page 11 of 11 Pages

                                   SIGNATURES

After reasonable inquiry and to the best of our knowledge and belief, the
undersigned certify that the information set forth in this statement is true,
complete and correct.


DATED:  July 17, 2006

                                       By: /s/ Scott A. Fine
                                           -----------------------------------
                                       Scott A. Fine, individually, and as
                                       member of Empire GP, L.L.C. and Empire
                                       Capital Management, L.L.C.



                                       By: /s/ Peter J. Richards
                                           -----------------------------------
                                       Peter J. Richards, individually, and as
                                       member of Empire GP, L.L.C. and Empire
                                       Capital Management, L.L.C.