New York, USA – July 18, 2022 – In recent decades, emerging infectious disease outbreaks such as severe acute respiratory syndrome (SARS) and H7N9 avian influenza have intensively harmed human health. COVID-19 represented a further emerging infection that was caused by SARS-CoV-2 at the end of 2019. Creative Biolabs, as a dedicated CRO specialized in antibody discovery, provides global customers with ViroAntibody engineering services and qualified antibody products to accelerate virology experiments and disease studies.
Diverse Methods Utilized in the Antibody Humanization Process
Recombinant antibody technology is becoming increasingly available and showing considerable clinical success. Meanwhile, antibody humanization is considered an alternative approach to mitigate undesirable immune responses. The antibody engineering team at Creative Biolabs provides independent, custom service packages for antibody humanization and advanced antibody platforms to ensure the best quality antibody solutions. “We will utilize a variety of methods and toolkits throughout the antibody humanization process,” according to a technician, “and our antibody humanization service is characterized by its low mutation rate (within six amino acids) that aims to minimize the immunogenicity of antibodies.”
Pseudovirus, a Valuable Virological Tool
Upon further research, it has been proved that pseudovirus can screen vaccines effectively on pathogenic viruses outside the BSL-3 or BSL-4 laboratory, which is a valuable virological tool for the evolving COVID-19. Creative Biolabs offers pseudoviruses generated by co-transfection 293T cells with a packaging vector, reporter vector, and a plasmid encoding specific virus proteins.
Pseudovirus products at Creative Biolabs suit the following applications:
* Pseudovirus-based inhibition assay for the detection of neutralizing antibodies
* Pseudovirus-based inhibition assay for the detection of anti-virus entry inhibitors
* Evaluating vaccine candidate-induced neutralizing antibodies against highly pathogenic viruses
SARS-CoV Antibodies Targeting Various Proteins
SARS-CoV is an enveloped, positive-sense single-stranded RNA virus, and evidently, it can infect epithelial cells within the lung through binding to the ACE2 receptor. SARS-CoV-2, another kind of coronavirus, has ignited the COVID-19 epidemic since December, 2019. Creative Biolabs provides a variety of SARS-CoV antibodies targeting various proteins, such as SARS-CoV spike proteins and SARS-CoV nucleocapsid proteins. Also, Creative Biolabs has developed antibodies to support the studies on COVID-19 as well as other viral pathogens.
More information about ViroAntibody solutions at Creative Biolabs can be found at https://viroantibody.creative-biolabs.com.
About Creative Biolabs
Creative Biolabs, armed with a group of highly educated experts, is committed to providing the highest quality ViroAntibody solutions for virologists, including but not limited to customized SARS-CoV antibodies targeting various proteins, antibody humanization, and pseudovirus.
Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-830-6441
Country: United States
Website: https://viroantibody.creative-biolabs.com